Fast and flexible analysis of linked microbiome data with mako.

Published in: Nature methods (2021)

Mako is a software tool that converts microbiome data and networks into a graph database and visualizes query results, thus allowing users without programming knowledge to carry out network-based queries. Mako is accompanied by a database compiled from 60 microbiome studies that is easily extended with the user's own data. We illustrate mako's strengths by enumerating association partners linked to propionate production and comparing frequencies of different network motifs across habitat types.

Keyphrases

electronic health record
big data
healthcare
climate change
data analysis
emergency department
machine learning
convolutional neural network
human immunodeficiency virus
case control