Immune cell profiles of metastatic HER2-positive breast cancer patients according to the sites of metastasis.

Tiia J HonkanenMilla E K LuukkainenAntti TikkanenPeeter KarihtalaMarkus MäkinenJuha P VäyrynenJussi Pekka Koivunen

Published in: Breast cancer research and treatment (2021)

Our results suggest that the site of metastasis is associated with prognosis in HER2-positive breast cancer, highlighted by the poor prognosis of liver metastases. Furthermore, liver metastases were associated with adverse tumour immune cell profiles.

Keyphrases

positive breast cancer
liver metastases
poor prognosis
long non coding rna
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
squamous cell carcinoma
prognostic factors
emergency department
electronic health record
patient reported