Blockade of alcohol excessive and "relapse" drinking in male mice by pharmacological cryptochrome (CRY) activation.

Yan ZhouMary Jeanne Kreek

Published in: Psychopharmacology (2021)

Pretreatment with KL001 (a CRY1/2 activator) reduces excessive and "relapse" alcohol drinking in mice. Our in vivo results with a CRY activator suggest a possible novel target for alcohol treatment intervention.

Keyphrases

alcohol consumption
nuclear factor
weight gain
randomized controlled trial
free survival
high fat diet induced
type diabetes
body mass index
adipose tissue
physical activity
skeletal muscle