Modulation of radiation-induced oral mucositis (mouse) by dermatan sulfate: effects on differentiation processes.

Nilsu Cini Sylvia GruberZumre Arican AlicikusWolfgang Dörr

Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2019)

The mucosal protective activity of DS, instead of stimulating proliferation, is based on prevention of cell loss by a combination of effects leading to the inhibition of cellular differentiation and an increase in the expression of epithelial mechanical strength between intercellular mechanical junctions.

Keyphrases

radiation induced
radiation therapy
poor prognosis
single cell
signaling pathway
cell therapy
stem cells
ulcerative colitis
mesenchymal stem cells
long non coding rna