Identification of hub genes in AR-induced tamoxifen resistance in breast cancer based on weighted gene co-expression network analysis.

Cao LuYang YangLi LingmeiHuang QiujuanGuo QianruQi LishaCao WenfengNiu YunPeisen Zhang

Published in: Breast cancer research and treatment (2022)

A high AR:ER expression ratio is a biomarker for patients who might develop TAM resistance, and AR expression seems to be a possible mechanism of resistance to endocrine therapy.

Keyphrases

network analysis
poor prognosis
genome wide
bioinformatics analysis
binding protein
breast cancer cells
diabetic rats
high glucose
endothelial cells
bone marrow
cell therapy