Risk factors and outcomes for the Q151M and T69 insertion HIV-1 resistance mutations in historic UK data.

Oliver T StirrupDavid T DunnAnna TostevinCaroline A SabinAnton PozniakDavid AsboeAlison CoxChloe OrkinFabiola MartinPatricia Canenull nullnull null

Published in: AIDS research and therapy (2018)

The Q151M and T69i resistance mutations are now very rare in the UK. Our results suggest that good outcomes are possible for people with these mutations. However, in this historic sample, viral load and CD4 at detection were important factors in determining prognosis.

Keyphrases

risk factors
antiretroviral therapy
hiv infected
human immunodeficiency virus
hepatitis c virus
hiv positive
cross sectional
electronic health record
hiv testing
type diabetes
big data
machine learning
adipose tissue
skeletal muscle
loop mediated isothermal amplification
insulin resistance
south africa