Randomized crossover trial to compare driving pressures in a closed-loop and a conventional mechanical ventilation mode in pediatric patients.

Gokhan CeylanSevgi TopalGulhan AtakulMustafa ColakEkin SoydanOzlem SandalFerhat SariHasan Ağın

Published in: Pediatric pulmonology (2021)

In this randomized crossover trial, ΔP in ASV 1.1 was lower compared to ΔP in physician-tailored APV-CMV mode in pediatric patients with different lung conditions. The use of ASV 1.1 may therefore result in continued, safe ventilation in a heterogeneous pediatric patient group.

Keyphrases

phase iii
mechanical ventilation
open label
placebo controlled
double blind
phase ii
study protocol
clinical trial
acute respiratory distress syndrome
intensive care unit
respiratory failure
emergency department
primary care
randomized controlled trial
extracorporeal membrane oxygenation
smoking cessation