Effectiveness of TRIzol in Inactivating Animal Pathogens.

Gwen DuytschaeverPatrícia R StröherKevin FonsecaFrank van der MeerAmanda Dawn Melin

Published in: Applied biosafety : journal of the American Biological Safety Association (2023)

Available evidence suggests that TRIzol Reagent is effective in inactivating a broad spectrum of bacteria and viruses from cells, tissues, and liquids in biological samples when the matrices are exposed to at least 10 min at room temperature to the reagent. We highlight areas that require additional research and discuss implications for laboratory protocols.

Keyphrases

room temperature
induced apoptosis
ionic liquid
cell cycle arrest
randomized controlled trial
systematic review
gene expression
endoplasmic reticulum stress
gram negative
signaling pathway
antimicrobial resistance
cell death