EGFR and PDL1: A Match (Not) Made in Heaven-A Real-World Retrospective Analysis of PDL1 Expression in EGFR-Mutated NSCLC.

Ullas BatraMansi SharmaShrinidhi NathanyAbhishek BansalSunil PasrichaParveen JainAnurag MehtaHarkirat Singh

Published in: Advances in therapy (2021)

The current study was an exploratory retrospective study; however, the results add to the growing body of evidence that PDL1 expression in EGFR-mutated NSCLC does not have any prognostic significance. Also the efficacy of EGFR TKIs is not influenced by variations in PDL1 TPS.

Keyphrases

small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
poor prognosis
advanced non small cell lung cancer
brain metastases
binding protein
long non coding rna