BRAF-positive multifocal and unifocal papillary thyroid cancer show different messenger RNA expressions.

Kyoungjune PakSunghwan SuhTae Sik GohSeong-Jang KimSae-Ock OhJu Won SeokIn Joo KimYun Hak Kim

Published in: Clinical endocrinology (2019)

Multifocal PTCs have higher expression of mRNAs in Wnt- and pluripotency-related pathways when BRAF mutation is present. This might be the mechanism that accounts for the difference between multifocal and unifocal PTCs.

Keyphrases

poor prognosis
metastatic colorectal cancer
stem cells
cell proliferation
embryonic stem cells
cell fate