One-year longitudinal association between changes in dietary choline or betaine intake association with cardiometabolic variables in the PREDIMED-Plus trial.
Laura Díez-RicoteRodrigo San-CristobalM José ConcejoMiguel Ángel Martínez-GonzálezDolores CorellaJordi Salas-SalvadóAlbert GodayJ Alfredo MartínezÁngel M Alonso-GómezJulia WärnbergJesús VioqueDora RomagueraJosé López-MirandaRamon EstruchFrancisco J TinahonesJosé LapetraJ Luís Serra-MajemAurora Bueno-CavanillasJosep A TurVicente Martín SánchezXavier PintoJosé Juan GaforioPilar Matía-MartínJosep VidalSebastián Mas FontaoEmili RosZenaida Vázquez-RuizCarolina Ortega-AzorínJesús F García-GavilánMireia MalcampoDiego Martínez-UrbistondoLucas Tojal-SierraAntonio García RodríguezNuria Gómez-BellvertAlice ChaplinAntonio García-RíosRosa M Bernal-LópezJosé Manuel Santos-LozanoJavier Basterra-GortariJosé V SorlíMichelle MurphyGriselda GasullaVíctor MicóItziar Salaverria-LeteEstibaliz Goñi OchandorenaNancy Elvira Babio SánchezXavier HerraizJosé M OrdovásLidia Daimiel RuizPublished in: The American journal of clinical nutrition (2022)
Increase in dietary choline or betaine intake were longitudinally related to improvements in cardiometabolic parameters. Markers of renal function were also slightly improved, and they required further investigation.