Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease.

Daniel LancourJosée DupuisRichard MayeuxJonathan L HainesMargaret A Pericak-VanceGerard C SchellenbergMark CrovellaLindsay A FarrerSimon Kasif

Published in: Alzheimer's research & therapy (2020)

Our findings indicate that AD-related risk factors are potentially associated with brain region-specific effects on gene expression that can be detected using a gene network approach.

Keyphrases

gene expression
risk factors
resting state
white matter
poor prognosis
dna methylation
functional connectivity
genome wide
mild cognitive impairment
copy number
single cell
multiple sclerosis
rna seq