FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression.

Zhen HeRong ZhangFeng JiangHong ZhangAihua ZhaoBo XuLi JinTao WangWei JiaWeiping JiaCheng Hu

Published in: Clinical epigenetics (2018)

Our findings suggest that genetic variants in the FADS region are major genetic modifiers that can regulate fatty acid metabolism through epigenetic gene regulation.

Keyphrases

fatty acid
dna methylation
gene expression
genome wide
copy number