Rethinking the "Pan-Culture": Clinical Impact of Respiratory Culturing in Patients With Low Pretest Probability of Ventilator-Associated Pneumonia.
Owen R AlbinLouis SaravolatzJoshua PetrieOryan HenigKeith S KayePublished in: Open forum infectious diseases (2022)
Performance of respiratory cultures for fever/leukocytosis in mechanically ventilated patients without increasing ventilator requirements, secretion burden, or radiographic evidence of pneumonia was associated with increased antibiotic use within 1 week after incident abnormal temperature and/or white blood cell count. Diagnostic stewardship interventions targeting performance of unnecessary respiratory cultures in mechanically ventilated patients may reduce antibiotic overuse within intensive care units.
Keyphrases
- intensive care unit
- end stage renal disease
- chronic kidney disease
- ejection fraction
- acute respiratory distress syndrome
- prognostic factors
- randomized controlled trial
- type diabetes
- stem cells
- mechanical ventilation
- clinical trial
- mesenchymal stem cells
- drug delivery
- cancer therapy
- respiratory failure
- study protocol