Neurally adjusted ventilatory assist vs. pressure support to deliver protective mechanical ventilation in patients with acute respiratory distress syndrome: a randomized crossover trial.
Fabia Diniz-SilvaHenrique T MoriyaAdriano M AlencarMarcelo B P AmatoCarlos R R CarvalhoJuliana Carvalho FerreiraPublished in: Annals of intensive care (2020)
It was feasible to keep VT in protective levels with NAVA and PSV for 75% of the patients. NAVA resulted in similar VT, RR and Paw compared to PSV. Our findings suggest that partial ventilatory assistance with NAVA and PSV is feasible as a protective ventilation strategy in selected ARDS patients under continuous sedation. Trial registration ClinicalTrials.gov (NCT01519258). Registered 26 January 2012, https://clinicaltrials.gov/ct2/show/NCT01519258.
Keyphrases
- mechanical ventilation
- acute respiratory distress syndrome
- end stage renal disease
- extracorporeal membrane oxygenation
- newly diagnosed
- intensive care unit
- chronic kidney disease
- ejection fraction
- clinical trial
- prognostic factors
- respiratory failure
- study protocol
- randomized controlled trial
- magnetic resonance imaging
- patient reported outcomes
- phase ii
- patient reported