Drug monitoring for mycophenolic acid in graft-vs-host disease prophylaxis in cord blood transplantation.

Hiroyuki MuranushiJunya KandaYasuyuki AraiTakero ShindoMasakatsu HishizawaTakashi YamamotoTadakazu KondoKohei YamashitaKazuo MatsubaraAkifumi Takaori-Kondo

Published in: British journal of clinical pharmacology (2020)

Blood level of MPA was associated with risk of acute GVHD and infection. A prospective trial evaluating the benefit of personalized MMF dosing using MPA levels is needed.

Keyphrases

cord blood
liver failure
respiratory failure
study protocol
phase iii
clinical trial
phase ii
drug induced
allogeneic hematopoietic stem cell transplantation
aortic dissection
cell therapy
stem cells
randomized controlled trial
hepatitis b virus
acute myeloid leukemia
mechanical ventilation