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Deciphering the genetic regulation of peripheral blood transcriptome in pigs through expression genome-wide association study and allele-specific expression analysis.

Tatiana MaroilleyG LemonnierJ LecardonnelD EsquerréY Ramayo-CaldasM J MercatC Rogel-GaillardJ Estellé
Published in: BMC genomics (2017)
This study represents, to the best of our knowledge, the first genome-wide map of the genetic control of gene expression in porcine peripheral blood. These results represent an interesting resource for the identification of genetic markers and blood biomarkers associated with variations in immunity traits in pigs, as well as any other complex traits for which blood is an appropriate surrogate tissue.
Keyphrases
  • genome wide
  • peripheral blood
  • dna methylation
  • gene expression
  • copy number
  • genome wide association study
  • poor prognosis
  • healthcare