Electroacupuncture Treatment Suppresses Transcription Factor IRF8 in Spinal Cord of Rats with Spared Nerve Injury.

Ying WangMeng XueYang-Yang XiaQian JiangZhi-Hua HuangCheng Huang

Published in: Pain research & management (2020)

This experiment highlighted that 2 Hz EA can inhibit IRF8 expression and microglial activation in the spinal cord of SNI rats. Hence, targeting IRF8 may be a promising therapeutic strategy for 2 Hz EA treatment of neuropathic pain.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
transcription factor
dendritic cells
poor prognosis
signaling pathway
inflammatory response
combination therapy
cancer therapy
brain injury
dna binding
replacement therapy