Expression of immune-related genes in rectum and colon descendens of Irritable Bowel Syndrome patients is unrelated to clinical symptoms.
Javier Aguilera-LizarragaMorgane V FlorensThomas Van BrusselEgbert CleversLukas Van OudenhoveDiether LambrechtsMira M WoutersGuy E BoeckxstaensPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)
A subset of IBS patients reveals evidence of immune activation in the colon descendens, but not in the rectum; however, gene expression is unrelated to clinical symptoms. To what extent this subgroup might however respond to anti-inflammatory therapy remains to be investigated.
Keyphrases
- end stage renal disease
- gene expression
- irritable bowel syndrome
- chronic kidney disease
- newly diagnosed
- ejection fraction
- prognostic factors
- anti inflammatory
- poor prognosis
- dna methylation
- patient reported outcomes
- depressive symptoms
- mesenchymal stem cells
- physical activity
- high resolution
- bone marrow
- smoking cessation
- study protocol