Dysregulation of MiR-30a-3p/Gastrin Enhances Tumor Growth and Invasion throughSTAT3/MMP11 Pathway in Gastric Cancer.

Yan LiuMeng GaoJuan AnXin WangYan JiaJunfeng XuJihai ZhuJiantao CuiWenmei LiRui XingLi SongKejia LiuYuqi HeJianqiu ShengShengmei QiYuanming PanYouyong Lu

Published in: OncoTargets and therapy (2020)

MiR-30a-3p was the promising suppressor gene through negatively regulating the expression of GAST, and dysregulation of GAST was a prognostic signature associated cell proliferation and metastasis through STAT3/MMP11 pathway in GC.

Keyphrases

cell proliferation
cell migration
poor prognosis
cell cycle
pi k akt
gene expression
transcription factor
genome wide identification
simultaneous determination