Connective Tissue Growth Factor Single Nucleotide Polymorphisms in (Familial) Pulmonary Fibrosis and Connective Tissue Disease Associated Interstitial Lung Disease.
Dymph KlayJoanne J van der VisSuzan M RoothaanTri Q NguyenJan C GruttersRoel GoldschmedingColine H M van MoorselPublished in: Lung (2021)
CTGF rs6918698G associates with spIPF and with FPF, but not with CTD-ILD in a Dutch cohort. CTGF is localized in lung tissue involved in IPF pathogenesis. Further research into the role of this SNP on CTGF expression and fibrogenesis is warranted.