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Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in the Elderly with Alzheimer's Disease (D-PRESCRIBE-AD): Trial protocol and rationale of an open-label pragmatic, prospective randomized controlled trial.

Sonal SinghNoelle M CocorosXiaojuan LiKathleen M MazorMary T AntonelliLauren E ParlettMark PaullinThomas P HarkinsYunping ZhouPaula A RochonRichard PlattInna DashevskyCarly MassinoCassandra SaphirakSybil L CrawfordJerry H Gurwitz
Published in: PloS one (2024)
This large pragmatic RCT will contribute to the evidence base on promoting deprescribing of potentially inappropriate medications among older adults with dementia. If successful, such light touch, inexpensive and highly scalable interventions have the potential to reduce the burden of potentially inappropriate prescribing for patients with dementia. ClinicalTrials.gov Identifier: NCT05147428.
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