Decreased Alpha Klotho Expression in Placentas Exposed to Severe Maternal Vascular Malperfusion.

Andrew D Franklin Alexa A FreedmanAnn BordersLauren Keenan DevlinErin S ProctorErica PriceSteve ColeGreg MillerLinda M Ernst

Published in: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society (2024)

Decreased AK gene and protein expression in the placenta in the setting of MVM is consistent with the theory of placental aging in MVM and is associated with increased odds of preterm birth.

Keyphrases

preterm birth
gestational age
birth weight
low birth weight
poor prognosis
genome wide
copy number
early onset
binding protein
pregnancy outcomes
gene expression
long non coding rna
aortic dissection
genome wide identification
pregnant women
body mass index
weight loss