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Development of a Rabbit Human Glioblastoma Model for Testing of Endovascular Selective Intra-Arterial Infusion (ESIA) of Novel Stem Cell-Based Therapeutics.

Peter T KanVisish M SrinivasanJoy GuminRoberto GarciaStephen R ChenJeremiah N JohnsonDalis E CollinsMelissa M ChenDaniel LedbetterJason T HuseZean Aaron Evan LunaAriadna RobledoViren VasandaniAbhijit RaoSanjay K SinghElizabeth J ShpallJuan FueyoCandelaria Gomez-ManzanoFrederick F Lang
Published in: Neuro-oncology (2023)
The intracranial immunosuppressed rabbit human GBM model allows testing of ESIA infusion of novel therapeutics (e.g., MSC-D24) in a clinically relevant fashion.
Keyphrases
  • endothelial cells
  • stem cells
  • low dose
  • small molecule
  • induced pluripotent stem cells
  • pluripotent stem cells
  • bone marrow
  • cell therapy
  • optic nerve