EMMPRIN expression is associated with metastatic progression in osteosarcoma.

Han-Soo KimHa Jeong KimMi Ra LeeIlkyu Han

Published in: BMC cancer (2021)

Our data suggest that EMMPRIN acts as a mediator of osteosarcoma metastasis by regulating MMP and VEGF production in cancer cells as well as stromal cells. EMMPRIN could serve as a therapeutic target in osteosarcoma.

Keyphrases

poor prognosis
squamous cell carcinoma
small cell lung cancer
endothelial cells
vascular endothelial growth factor
big data
cell migration