Longitudinal White Matter Damage Evolution in Parkinson's Disease.
Pietro Giuseppe ScamarciaFederica AgostaEdoardo Gioele SpinelliSilvia BasaiaTanja StojkovićIva StankovicElisabetta SarassoElisa CanuVladana MarkovicIgor PetrovićElka StefanovaElisabetta PaganiVladimir S KosticMassimo FilippiPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
Our study suggests an association between WMHs and cognitive deterioration in PD, whereas WM microstructural damage is a negligible contributor to clinical deterioration. WMHs assessed by MRI can provide an important tool for monitoring the development of cognitive impairment in PD patients. © 2021 International Parkinson and Movement Disorder Society.