Estimating relative risks in multicenter studies with a small number of centers - which methods to use? A simulation study.
Claudia PedrozaVan Thi Thanh TruongPublished in: Trials (2017)
For the analyses of multicenter studies with a binary outcome and few centers, we recommend adjustment for center with either a GEE log-binomial or Poisson model with appropriate small sample corrections or a Bayesian binomial GLMM with informative priors.