Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition.
Camille Vanessa EdwardsGrace M FerriJosue Villegas-GalavizSabrina GhoshPushpinder Singh BawaFeiya WangElena KlimtchukTinuola B AjayiGareth J MorganTatiana ProkaevaAndrew StaronFrederick L RubergVaishali SanchorawalaRichard M GiadoneGeorge J MurphyPublished in: bioRxiv : the preprint server for biology (2024)
Collectively, our findings highlight early molecular and functional signatures of cardiac AL amyloidosis, with potential impact for developing improved patient biomarkers and novel therapeutics.