Multi-Institutional Study Evaluating the Role of Circulating Tumor DNA in the Management of Appendiceal Cancers.
Erika BelmontVarun V BansalMahmoud M G YousefMohammad A ZeineddineDavid G SuAnkit DhimanChih-Yi LiaoBlasé N PoliteOliver S EngKeith F FournierMichael G WhiteKiran Kalyan TuragaJohn Paul ShenArdaman ShergillPublished in: JCO precision oncology (2024)
This study revealed a reduced ctDNA detection frequency after systemic therapy and accurate recurrence assessment after CRS. These findings underscore the role of ctDNA as a predictive and prognostic biomarker for grade 2-3 AC-PM management.