Prognostic value of pathological lymph node status and primary tumour regression grading following neoadjuvant chemotherapy - results from the MRC OE02 oesophageal cancer trial.
Nasser DavarzaniGordon G A HutchinsNicholas P WestLindsay C HewittMatthew NankivellDavid CunninghamWilliam H AllumElizabeth SmythNicola ValeriRuth E LangleyHeike I GrabschPublished in: Histopathology (2018)
Lymph node status post-NAC is the most important prognostic factor in patients with resectable oesophageal cancer, irrespective of TRG. Potential clinical implications, e.g. adjuvant treatment or intensified follow-up, reinforce the importance of LN dissection for staging and prognostication.