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Grouping of genomic markers in populations with family structure.

Dörte WittenburgMichael DoschorisJan Klosa
Published in: BMC bioinformatics (2021)
Chromosome segments which frequently recombine in the underlying population can be identified from the matrix of pairwise dependence between markers. Representative markers can be exploited, for instance, for dimension reduction prior to a genome-based association study or the grouping structure itself can be employed in a grouped penalization approach.
Keyphrases
  • genome wide
  • cross sectional
  • dna methylation