Allogeneic hematopoietic stem cell transplantation in r/r Hodgkin lymphoma after treatment with checkpoint inhibitors: Feasibility and safety.
Reyad DadaBinyam UsmanPublished in: European journal of haematology (2018)
This is the largest pooled analysis of its kind published so far. Our results suggest that allogeneic HSCT after CPIs is feasible and not associated with higher mortality. However, careful consideration should be given for prevention, early detection, and effective treatment of GVHD in these cases. Additional prospective studies are needed for further clarification.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- hodgkin lymphoma
- acute myeloid leukemia
- acute lymphoblastic leukemia
- stem cell transplantation
- hematopoietic stem cell
- dna damage
- cardiovascular events
- cell cycle
- bone marrow
- type diabetes
- randomized controlled trial
- cardiovascular disease
- risk factors
- systematic review
- cell proliferation
- low dose
- combination therapy
- coronary artery disease
- case control
- meta analyses
- high dose
- smoking cessation
- replacement therapy