The Long Non-Coding RNA-14327.1 Promotes Migration and Invasion Potential of Endometrial Carcinoma Cells by Stabilizing the Potassium Channel Kca3.1.

Yingli ZhangPing ZhangLu ChenLingqin ZhaoJian Qing Zhu Tao Zhu

Published in: OncoTargets and therapy (2019)

Taken together, our results demonstrated that the lncRNA-14327.1 promoted cell migration and invasion potential of endometrial carcinoma cells by stabilizing Kca3.1 protein, implying that the lncRNA-14327.1/Kca3.1 might be a promising therapeutic target in endometrial carcinoma, particularly the metastatic one.

Keyphrases

long non coding rna
poor prognosis
endometrial cancer
squamous cell carcinoma
single cell
human health
cell therapy
stem cells
risk assessment
bone marrow
small molecule
binding protein