[ 131 I]6ß-Iodomethyl-19-norcholesterol SPECT/CT for the Lateralization of Mineralocorticoid Overproduction in Primary Aldosteronism.
Sandor BarnaLivia SiraHarjit Pal BhattoaLaszlo TothZsigmond CzineLilla SzoboszlayEdit B NagyZita KepesIldiko GaraiMiklos BodorJózsef VargaEndre Vezekenyi NagyPublished in: Diagnostics (Basel, Switzerland) (2024)
I]6ß-iodomethyl-19-norcholesterol SPECT/CT with a count-based image interpretation and side-ratio calculation may be an equipollent non-invasive substitute for adrenal venous sampling in the lateralization of mineralocorticoid overproduction. It reliably identifies unilateral disease and facilitates patients' selection for surgical intervention. If confirmed by others, this functional imaging may replace AVS when lateralization is required for management decisions in primary aldosteronism.
Keyphrases
- end stage renal disease
- computed tomography
- image quality
- ejection fraction
- randomized controlled trial
- newly diagnosed
- dual energy
- contrast enhanced
- chronic kidney disease
- high resolution
- pet ct
- prognostic factors
- genome wide
- peritoneal dialysis
- magnetic resonance imaging
- gene expression
- machine learning
- magnetic resonance
- dna methylation
- peripheral blood
- photodynamic therapy