Long-term proton pump inhibitor use and risk of osteoporosis and hip fractures: A nationwide population-based and multicenter cohort study using a common data model.
Da Hee ParkSeung In SeoKyung Joo LeeJinseob KimYerim KimWon-Woo SeoHyung Seok LeeWoon Geon ShinJong Jin YooPublished in: Journal of gastroenterology and hepatology (2022)
Long-term PPI was significantly associated with osteoporosis; however, the results of hip fractures were inconsistent. Further study based on better data quality may be needed.