Multicenter Comparison of the Etest and EUCAST Methods for Antifungal Susceptibility Testing of Candida Isolates to Micafungin.
M-E BougnouxEric DannaouiI AccoceberryA AngoulvantE BaillyF BotterelS ChevrierT ChouakiMurielle CornetF DalleA DatryA DupuisA FekkarJ P GangneuxJ GuitardC HennequinY Le GovicP Le PapeD MaubonStéphane RanqueM SautourB SendidJ ChandenierPublished in: Antimicrobial agents and chemotherapy (2016)
In vitro susceptibility of 933 Candida isolates, from 16 French hospitals, to micafungin was determined using the Etest in each center. All isolates were then sent to a single center for determination of MICs by the EUCAST reference method. Overall essential agreement between the two tests was 98.5% at ±2 log2 dilutions and 90.2% at ±1 log2 dilutions. Categorical agreement was 98.2%. The Etest is a valuable alternative to EUCAST for the routine determination of micafungin MICs in medical mycology laboratories.