Surgery compared to fibrinolytic therapy for symptomatic left-sided prosthetic heart valve thrombosis (SAFE-PVT): Rationale and design of a randomized controlled trial.
Niveditha DevasenapathyVelayoudam DevagourouMilind P HotePalleti RajashekarBharathraj KidambiAayush SingalMohsin Raj MantooManoj SoniGaurav PurohitSandeep SinghGanesan KarthikeyanPublished in: Indian heart journal (2024)
This is the first randomized trial to compare urgent surgery with FT for the treatment of left-sided PVT. The results will provide evidence to help clinicians make treatment choices for these patients. (Clinical trial registration: CTRI/2017/10/010159).
Keyphrases
- clinical trial
- minimally invasive
- coronary artery bypass
- end stage renal disease
- ejection fraction
- newly diagnosed
- palliative care
- randomized controlled trial
- mitral valve
- prognostic factors
- aortic stenosis
- atrial fibrillation
- study protocol
- patient reported outcomes
- percutaneous coronary intervention
- transcatheter aortic valve replacement
- phase iii