Direct liquid extraction surface analysis mass spectrometry of cell wall lipids from mycobacteria: Salt additives for decreased spectral complexity.
Alexander N ConnerJessie R JarvisLuke J AlderwickRian L GriffithsPublished in: Rapid communications in mass spectrometry : RCM (2019)
LESA offers a sensitive technique for bacterial lipid phenotyping. The inclusion of an acetate salt in the sampling solvent drives adduct formation towards a specific adduct type and thus significantly reduces spectral complexity.