Effect of genetic polymorphisms rs2301113 and rs2057482 in the expression of HIF-1α protein in periodontal ligament fibroblasts subjected to compressive force.
Erika Calvano KüchlerVinicius Broska TeodoroAgnes SchröderUte NazetMichelle Nascimento MegerPatricia Valéria Manozzo KunzFlares Baratto FilhoGerrit SpanierRafaela ScariotPeter ProffChristian KirschneckPublished in: Journal of applied oral science : revista FOB (2023)
Our study confirms that compressive pressure application enhances HIF-1α protein expression. We could not prove that the genetic polymorphisms in HIF1A affect HIF-1α protein expression by periodontal ligament fibroblasts during simulated orthodontic compressive force.