Physiologically based radiopharmacokinetic (PBRPK) modeling to simulate and analyze radiopharmaceutical therapies: studies of non-linearities, multi-bolus injections, and albumin binding.

Ali Fele-ParanjBabak SabouryCarlos UribeXinchi Hou

Published in: EJNMMI radiopharmacy and chemistry (2024)

Advanced computational PBRPK modeling enables simulation and analysis of a variety of intervention and drug design scenarios, towards more optimal delivery of RPTs.

Keyphrases

randomized controlled trial
climate change
emergency department
ultrasound guided
case control
platelet rich plasma
binding protein
virtual reality
transcription factor