PM2.5 Induces the Expression of Inflammatory Cytokines via the Wnt5a/Ror2 Pathway in Human Bronchial Epithelial Cells.

Weifeng ZouXiaoqian WangWei HongFang HeJinxing HuQing ShengTao ZhuPixin Ran

Published in: International journal of chronic obstructive pulmonary disease (2020)

PM2.5 induces the secretion of IL-6, IL-8 and IL-1β in HBECs via the Wnt5a/Ror2 signaling, demonstrating a novel mechanism for PM2.5-associated airway inflammation.

Keyphrases

particulate matter
air pollution
polycyclic aromatic hydrocarbons
heavy metals
stem cells
cell proliferation
endothelial cells
poor prognosis
water soluble
induced pluripotent stem cells
binding protein
risk assessment