Generational changes in multiple sclerosis phenotype in North African immigrants in France: A population-based observational study.

Clotilde NardinClotilde LatarcheMarc SoudantCamille DahanMaud MichaudSophie Pittion-VouyovitchFrancis GuilleminMarc DebouverieGuillaume Mathey

Published in: PloS one (2018)

We found two different phenotypes among NAG1 and NAG2 MS patients in France. NAG1, but not NAG2, have a higher risk of disability than Europeans. This raises the question of environmental factors in MS expression, and advocates appropriate patient management according to generation in immigrants.

Keyphrases

multiple sclerosis
end stage renal disease
mass spectrometry
ejection fraction
newly diagnosed
ms ms
chronic kidney disease
poor prognosis
white matter
prognostic factors
peritoneal dialysis
tertiary care
binding protein