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The application value of metagenomic next-generation sequencing technology in the diagnosis and treatment of neonatal infectious meningitis - a single center retrospective case-control study.

Yun-Su ZouZhao-Lan CaoYan GuoBei-Bei WangJia-Li WangRui ChengYang YangXiao-Guang Zhou
Published in: Neurological research (2024)
Compared with classic meningitis detection methods, mNGS has better PPV, NPV, agreement rate, and AUC. mNGS could help improve the cure rate.
Keyphrases
  • cerebrospinal fluid
  • cross sectional
  • copy number
  • loop mediated isothermal amplification
  • label free
  • circulating tumor
  • microbial community
  • genome wide
  • cell free