Prognostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in newly diagnosed multiple myeloma: a systematic review and meta-analysis.
Sangwon HanSungmin WooYong-Il KimDok Hyun YoonJin-Sook RyuPublished in: European radiology (2020)
• There remain unmet clinical needs for reliable prognostic biomarkers in patients with newly diagnosed multiple myeloma. • This meta-analysis shows that the presence of extramedullary disease, more than three focal lesions, and high FDG uptake from baseline 18F-FDG PET are significant prognostic factors. • These imaging biomarkers might help the accurate stratification of patient prognosis which is required for choosing an appropriate therapeutic strategy in clinical practice.
Keyphrases
- positron emission tomography
- newly diagnosed
- multiple myeloma
- prognostic factors
- computed tomography
- systematic review
- clinical practice
- pet imaging
- pet ct
- high resolution
- magnetic resonance imaging
- case report
- meta analyses
- contrast enhanced
- randomized controlled trial
- image quality
- photodynamic therapy
- mass spectrometry
- fluorescence imaging