ANGPTL4 Suppresses Clear Cell Renal Cell Carcinoma via Inhibition of Lysosomal Acid Lipase.

Zeng Jin Umasankar De Tanzia Islam Tithi Jeremy Kleberg Akhila Nataraj Elena Jolley Madison E Carelock Brandon S J Davies Weizhou Zhang Ryan Kolb

Published in: Cancer research communications (2024)

Our data indicate angiopoietin-like 4 (ANGPTL4) acts as a tumor suppressor in clear cell renal cell carcinoma via regulating lipid metabolism and identifies a cohort of patients with lower expression of ANGPTL4 that are correlated with shorter survival.

Keyphrases

poor prognosis
signaling pathway
electronic health record
gene expression
machine learning
deep learning