Reporting Rates of Opioid-Related Adverse Events Since 1965 in Canada: A Descriptive Retrospective Study.
Maude LavalléeCarolina Galli da SilveiraSamuel AkinolaJulie MéthotMarie-Eve PichéAnick BérardMagalie ThibaultJennifer Midiani GonellaFernanda Raphael Escobar GimenesJacinthe LeclercPublished in: Drugs - real world outcomes (2021)
Reported opioid-related ARs have increased since 1965, although fluctuations were observed in recent decades. The absolute number of opioid-related ARs might be seriously underestimated. Future studies should look into how to close this gap.