Automated computed tomography quantification of fibrosis predicts prognosis in combined pulmonary fibrosis and emphysema in a real-world setting: a single-centre, retrospective study.
Masahiro NemotoYuichiro NeiBrian BartholmaiKazuki YoshidaHiroki MatsuiTamao NakashitaShinji MotojimaMasahiro AoshimaJay H RyuPublished in: Respiratory research (2020)
Less severe (< 5%) fibrosis at baseline was associated with disease stability and better prognosis compared to more severe fibrosis in CPFE occurring with fibrotic ILDs. Further studies including a validation cohort will be needed. Trial Registration Retrospectively registered.
Keyphrases
- pulmonary fibrosis
- computed tomography
- early onset
- idiopathic pulmonary fibrosis
- liver fibrosis
- magnetic resonance imaging
- chronic obstructive pulmonary disease
- machine learning
- study protocol
- deep learning
- high throughput
- systemic sclerosis
- randomized controlled trial
- lung function
- magnetic resonance
- phase ii
- contrast enhanced
- drug induced
- dual energy
- open label
- cystic fibrosis