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Long-term clinical efficacy of topical treatment with recombinant human nerve growth factor in neurotrophic keratopathy: a novel cure for a rare degenerative corneal disease?

Alice BruscoliniMarco MarencoGiuseppe Maria AlbaneseAlessandro LambiaseMarta Sacchetti
Published in: Orphanet journal of rare diseases (2022)
A single 8-week treatment regimen of Cenegermin eye drops has clinical efficacy that can persist for up to 48 months. The long-term clinical utility of treatment with Cenegermin for NK was demonstrated through the low rate of lesion recurrence along with improvements in corneal sensitivity and tear production.
Keyphrases
  • growth factor
  • recombinant human
  • randomized controlled trial
  • clinical trial
  • optical coherence tomography
  • replacement therapy