Soluble CD163 correlates with lipid metabolic adaptations in type 1 diabetes patients during ketoacidosis.

Mads Vandsted SvartNikolaj RittigNiels MøllerHolger J MøllerHenning Gronbaek

Published in: Journal of diabetes investigation (2018)

Macrophage activation assessed by sCD163 might play an important role in DKA, as it correlates strongly with important components of lipid metabolism including free fatty acids, palmitate, lipid oxidation, G0/G1 switch 2 gene and pro-inflammatory cytokines during initial steps of DKA. These results are novel and add important knowledge to the field of DKA.

Keyphrases

fatty acid
type diabetes
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
healthcare
peritoneal dialysis
prognostic factors
hydrogen peroxide
genome wide
gene expression
copy number
glycemic control
nitric oxide
dna methylation
metabolic syndrome
skeletal muscle
visible light