Postnatal ex vivo rat model for longitudinal bone growth investigations.

Adamu Abdul AbubakarSahar Mohammed IbrahimAhmed Khalaf AliKareem Obayes HandoolMohammad Shuaib KhanMohamed Noordin MustaphaTengku Azmi IbrahimUbedullah KakaLoqman Mohamad Yusof

Published in: Animal models and experimental medicine (2019)

Ex vivo growth of tibia and metatarsal bones of rats aged 7-15 days old is possible, with percentage growth rates of 23.87 ± 0.80% and 40.38 ± 0.95% measured in tibia and metatarsal bone, respectively. Histological sectioning of bones was carried out without the need for decalcification in P7-P13 tibia and P7-P15 metatarsal bone. Increases in chondrocyte density along the GP influence overall bone elongation.

Keyphrases

bone mineral density
soft tissue
bone loss
bone regeneration
postmenopausal women
cross sectional